Overview
What is it?
Low-level laser therapy (LLLT), also known as photobiomodulation therapy, is a non-invasive treatment that uses low-intensity red or near-infrared light to stimulate cellular activity and promote tissue repair and regeneration. It is not naturally occurring but is a therapeutic technique developed for medical and cosmetic purposes.
How does it work?
LLLT works by delivering light energy to the scalp, which is absorbed by cells in the hair follicles. This process, called photobiomodulation, enhances mitochondrial activity, increases ATP production, and reduces oxidative stress. These effects stimulate dormant hair follicles, shifting them from the resting (telogen) phase to the active growth (anagen) phase, promoting hair regrowth .
What are the benefits?
LLLT has been shown to stimulate hair growth in both men and women with conditions like androgenetic alopecia (AGA), alopecia areata (AA), and even chemotherapy-induced hair loss. It is safe, non-invasive, and effective, with studies reporting increased hair density, improved hair regrowth, and high patient satisfaction .
Effectiveness
What does the research say?
Research supports the use of LLLT for hair loss. Clinical trials have demonstrated significant increases in hair density and hair count. For example, one study showed a 12-17% increase in hair count after 26 weeks of treatment with LLLT devices. Another study found that LLLT combined with minoxidil was more effective than either treatment alone .
Side Effects
Scalp tenderness
Some users may experience mild tenderness or discomfort on the scalp during or after treatment.
Temporary hair shedding (telogen effluvium)
In the first 1-2 months of treatment, temporary hair shedding may occur as hair follicles transition to the growth phase.
Mild urticaria (hives)
Rarely, some individuals may develop mild hives or skin irritation.
Paresthesia (tingling sensation)
A tingling or prickling sensation on the scalp has been reported in a few cases.
Evidence
Clinical Studies & Trials
[1] Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considerations, and ethics.
This review discusses various treatments for androgenetic alopecia, including PRP and LLLT, highlighting their efficacy and side effects.
View study[2] Female pattern hair loss: A comprehensive review.
This paper reviews the pathophysiology, diagnosis, and treatments for female pattern hair loss, including LLLT.
View study[3] Photobiomodulation: The Clinical Applications of Low-Level Light Therapy.
This review explores the mechanisms and clinical applications of LLLT, including its use in hair regrowth.
View study[4] New Treatments for Hair Loss.
This review summarizes new treatments for hair loss, including LLLT, and discusses their efficacy and mechanisms.
View study[5] Low-level laser (light) therapy (LLLT) for treatment of hair loss.
This review provides an in-depth analysis of LLLT for hair loss, including its mechanisms, benefits, and side effects.
View study[6] Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs.
This paper reviews current treatments for androgenetic alopecia, including PRP and LLLT, and discusses their efficacy and limitations.
View study[7] Exosome therapy in hair regeneration: A literature review of the evidence, challenges, and future opportunities.
This review explores the role of exosomes in hair regeneration and their potential as a treatment for alopecia.
View study[8] The effectiveness of treatments for androgenetic alopecia: A systematic review and meta-analysis.
This meta-analysis evaluates the effectiveness of treatments for androgenetic alopecia, including LLLT.
View study[9] What's New in Therapy for Male Androgenetic Alopecia?
This review discusses new treatments for male androgenetic alopecia, including LLLT and PRP.
View study[10] Status of research on the development and regeneration of hair follicles.
This review explores the mechanisms of hair follicle regeneration, including the role of LLLT.
View study[11] Prevention and Treatment of Chemotherapy-Induced Alopecia: What Is Available and What Is Coming?
This review discusses treatments for chemotherapy-induced alopecia, including LLLT.
View study[12] Role of Low-Level Light Therapy (LLLT) in Androgenetic Alopecia.
This review evaluates the efficacy of LLLT in treating androgenetic alopecia, highlighting its safety and effectiveness.
View study[13] Photobiomodulation therapy in management of cancer therapy-induced side effects: WALT position paper 2022.
This position paper discusses the use of photobiomodulation therapy for managing side effects of cancer therapy, including its safety and mechanisms.
View study