Pumpkin Seed Oil

What does the research say?

Research supports the effectiveness of pumpkin seed oil for treating hair loss. A randomized, double-blind, placebo-controlled trial involving 76 men with mild to moderate androgenetic alopecia found that participants who took 400 mg of pumpkin seed oil daily for 24 weeks experienced a 40% increase in hair count, compared to a 10% increase in the placebo group. Another study on mice showed that topical application of pumpkin seed oil significantly increased the number of hair follicles and reversed hair growth retardation caused by testosterone [6] [14] .

Mild abdominal discomfort

Some individuals may experience mild abdominal discomfort after consuming pumpkin seed oil, though this is rare [6] .

Whole body itching sensation

A few users have reported a temporary itching sensation across the body, which typically resolves on its own [6] .

[1] Natural products for male androgenetic alopecia.

This review explores the potential of natural products, including pumpkin seed oil, for treating male androgenetic alopecia (AGA). It highlights the limitations of conventional treatments like minoxidil and finasteride and suggests natural alternatives.

[2] Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair Loss: A Systematic Review.

This systematic review examines the safety and effectiveness of nutritional supplements, including pumpkin seed oil, for treating hair loss. It emphasizes the need for more research to confirm their efficacy.

[3] Complementary and alternative supplements: a review of dermatologic effectiveness for androgenetic alopecia.

This review discusses the role of natural supplements, including pumpkin seed oil, in treating androgenetic alopecia. It highlights the antiandrogenic and antioxidant properties of pumpkin seed oil.

[4] Pumpkin seed oil vs. minoxidil 5% topical foam for the treatment of female pattern hair loss: A randomized comparative trial.

This study compares the effectiveness of pumpkin seed oil and minoxidil 5% foam in treating female pattern hair loss. It highlights the potential of pumpkin seed oil as a natural alternative.

[5] The Use of Natural Ingredients in the Treatment of Alopecias with an Emphasis on Central Centrifugal Cicatricial Alopecia: A Systematic Review.

This review explores the use of natural ingredients, including pumpkin seed oil, for treating various types of alopecia. It highlights the antiandrogenic effects of pumpkin seed oil.

[6] Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial.

This clinical trial demonstrates the effectiveness of pumpkin seed oil in increasing hair count and thickness in men with androgenetic alopecia. Participants who took 400 mg of pumpkin seed oil daily for 24 weeks experienced a 40% increase in hair count.

[7] Commonly used hair oils in the Black community: a narrative review in their use to treat androgenetic alopecia.

This review examines the use of hair oils, including pumpkin seed oil, in the Black community for treating androgenetic alopecia. It highlights the growing popularity of natural oils for hair care.

[8] Emerging and traditional 5-α reductase inhibitors and androgen receptor antagonists for male androgenetic alopecia.

This review discusses the limitations of traditional treatments for androgenetic alopecia and explores alternative treatments, including pumpkin seed oil, which inhibits 5-alpha reductase.

[9] An Overview of Commonly Used Natural Alternatives for the Treatment of Androgenetic Alopecia, with Special Emphasis on Rosemary Oil.

This review highlights the benefits of natural alternatives, including pumpkin seed oil, for treating androgenetic alopecia. It emphasizes the role of pumpkin seed oil in inhibiting 5-alpha reductase and promoting hair growth.

[10] Comment on 'Effect of Pumpkin Seed Oil on Hair Growth in Men with Androgenetic Alopecia: A Randomized, Double-Blind, Placebo-Controlled Trial'.

This paper comments on a study by Cho et al. (2014) and suggests that pumpkin seed oil shows promise for treating androgenetic alopecia but calls for more research, particularly on frontal hair loss.

[11] Evaluation of the efficacy and toxicity of oral and topical pumpkin oil on the hair growth of mice.

This study evaluates the efficacy and safety of pumpkin seed oil in promoting hair growth in mice. It found that pumpkin seed oil increased hair follicle proliferation without causing toxicity.

[12] Pumpkin Seed Oil-Loaded Niosomes for Topical Application: 5α-Reductase Inhibitory, Anti-Inflammatory, and In Vivo Anti-Hair Loss Effects.

This study demonstrates that pumpkin seed oil-loaded niosomes improve skin permeation, inhibit 5-alpha reductase, and reduce hair loss. It showed a 44.42% reduction in fallen hairs after 8 weeks of treatment.

[13] Niosomal delivery of pumpkin seed oil: development, characterisation, and physical stability.

This study focuses on the development of niosomes encapsulated with pumpkin seed oil for topical delivery. It highlights the potential of pumpkin seed oil in treating hair loss and other health conditions.

[14] Beneficial effects of pumpkin seed oil as a topical hair growth promoting agent in a mice model.

This study shows that topical application of pumpkin seed oil significantly increases hair growth in mice and reverses hair growth retardation caused by testosterone. It also increases the percentage of hair follicles in the anagen phase.