Overview
What is it?
Topical erythromycin and benzoyl peroxide are commonly used treatments for acne. Erythromycin is an antibiotic that helps reduce the bacteria (Cutibacterium acnes) on the skin, while benzoyl peroxide is a topical agent that kills bacteria, reduces inflammation, and helps unclog pores. These two ingredients are often combined in a single formulation to enhance their effectiveness in treating acne.
How does it work?
Erythromycin works by inhibiting the growth of acne-causing bacteria on the skin, reducing inflammation and preventing new breakouts. Benzoyl peroxide, on the other hand, works by releasing oxygen into the pores, which kills bacteria and helps remove dead skin cells and excess oil. When used together, they provide a dual-action approach: erythromycin targets the bacteria, and benzoyl peroxide prevents bacterial resistance and keeps pores clear .
What are the benefits?
The combination of topical erythromycin and benzoyl peroxide offers several benefits for acne treatment. It is effective against both inflammatory and non-inflammatory acne, helping to reduce redness, swelling, and the number of pimples. This combination also minimizes the risk of antibiotic resistance, which can occur with the use of antibiotics alone. Additionally, it is considered safe for use during pregnancy when prescribed by a healthcare provider .
Effectiveness
What does the research say?
Research shows that the combination of topical erythromycin and benzoyl peroxide is highly effective for treating acne. Studies indicate that this combination reduces both inflammatory and non-inflammatory lesions, with improved outcomes compared to using either ingredient alone. It is particularly recommended for inflammatory acne, as it targets the bacteria and reduces inflammation simultaneously .
Side Effects
Skin irritation
Skin irritation: Some users may experience mild irritation, especially when first starting treatment .
Dryness
Dryness: Benzoyl peroxide can cause the skin to become dry, so moisturizing is recommended .
Redness
Redness: Temporary redness may occur, particularly in sensitive skin types .
Peeling
Peeling: Mild peeling or flaking of the skin can happen as the treatment works to unclog pores .
Burning or stinging sensation
Burning or stinging sensation: This is usually mild and temporary, but if it persists, consult a healthcare provider .
Evidence
Clinical Studies & Trials
[1] Guidelines of care for the management of acne vulgaris.
This guideline provides recommendations for managing acne vulgaris, which commonly affects adults, adolescents, and preadolescents aged 9 years or older.
View study[2] Guidelines of care for the management of acne vulgaris.
This evidence-based guideline addresses the management of acne, including grading and treatment options, with a focus on topical and systemic therapies.
View study[3] Management of Acne in Pregnancy.
This review discusses the safety and efficacy of acne treatments during pregnancy, including topical options like benzoyl peroxide and erythromycin.
View study[4] Treatment of Acne in Pregnancy.
This paper outlines safe and effective treatments for acne during pregnancy, including the use of topical erythromycin and benzoyl peroxide.
View study[5] Acne vulgaris.
This review discusses the use of topical antibiotics and retinoids for acne treatment, including their mechanisms and side effects.
View study